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1.
AIP Conference Proceedings ; 2714, 2023.
Article in English | Scopus | ID: covidwho-20243501

ABSTRACT

The rapid global spread of the Covid-19 led to the utilization of online tools for various lecturing activities. Online learning is a change mandated on lecturers and students to achieve significant educational goals, irrespective of time and location. This research investigates factors affecting the use of the videoconferencing app, Zoom in supporting the online lectures. This study is quantitative research with the unified theory of acceptance and the use of technology (UTAUT) model to analyze online learning software acceptance. The research subjects consist of students and lecturers from the University of Bina Sarana Informatika (UBSI) Indonesia. The result shows that the performance and effort expectancies, as well as the social factors, affect users' attitude towards the software use and their behavioral intention. Also, the facilitating conditions affect their attitude with no significant effect on intention. © 2023 Author(s).

2.
AIP Conference Proceedings ; 2595, 2023.
Article in English | Scopus | ID: covidwho-20240531

ABSTRACT

Essential oil could be used as traditional medicine (aromatherapy) for the respiratory system by inhalation and ingestion. Lavender, peppermint, and eucalyptus essential oils are potentially beneficial to treat and relieve diseases symptoms caused by viruses and respiratory disorders, such as Covid-19. Using Brine Shrimp Lethality Test, this study aimed to determine the LC50 of lavender, peppermint, and eucalyptus essential oil. The essential oils were produced from a refining factory. The concentrations of each sample solution used were 1, 10, 20, 40, 60, and 80 ppm. The solutions were poured into ten Artemia salina leach and then incubated for 24 hours. LC50 of essential oils was obtained by determining the mortality percentage and probity analysis. The analysis showed that the LC50 of Lavender was 151.2 ppm, the LC50 of peppermint was 101.9 ppm, and the LC50 of eucalyptus was 105.7 ppm;all were toxic. © 2023 Author(s).

3.
Economies ; 11(5), 2023.
Article in English | Web of Science | ID: covidwho-20235562

ABSTRACT

The global COVID-19 pandemic has suppressed the economy and people's welfare, including in Indonesia and Central Java Province, as indicated by the weakening of the national economy by -2.06 percent and locally by -2.65 percent in 2020. Although the economy grew by 3.32 percent in 2021, societal welfare remains lower than in 2019, marked by an increase in unemployment and poverty throughout 2019-2021. Furthermore, the threat of COVID-19 including new variants of the virus continues to weigh on the economy, in 2022 and beyond. This study considered an industrial approach to production, based on inter-industrial linkages and policy simulations with input-output analysis. The objectives of this research are to analyze the impact of the COVID-19 pandemic on the economy of Central Java and to formulate an effective economic recovery policy for industry. The results show that the industries affected by the COVID-19 pandemic in Central Java can promote recovery of overall income in economic industry better than the leading industry and the industries with the highest output multipliers, expressed as a proportional increase in final demand for each industry. Meanwhile, the economic recovery strategy of increasing final demand in industries with high output multipliers results in a faster increase in economic output compared with increasing final demand in the affected industries or leading industries.

4.
Lett Spat Resour Sci ; 16(1): 26, 2023.
Article in English | MEDLINE | ID: covidwho-20240636

ABSTRACT

The COVID-19 pandemic has hit urban areas particularly hard, yet there is a lack of research on the hypothesis that living in more compact cities can provide better support for work and social conditions during the pandemic. This study addresses this gap by examining whether city compactness can mitigate the negative impact of the pandemic on the work and social life of urban residents in Jakarta, Indonesia. The study uses a household phone survey combined with publicly available urban form data. Ordinary Least Squares (OLS) regression, supplemented with a matching technique to address potential selection bias, is employed. The results suggest that living in more compact locations can reduce the disruption to work and social life associated with COVID-19 in urban communities. This positive effect is particularly experienced by males, non-migrants, and individuals from wealthy families.

5.
Calitatea ; 24(192):68-72, 2023.
Article in English | ProQuest Central | ID: covidwho-2327302

ABSTRACT

To achieve their investment objectives, each investor has a strategy in place. A high amount of personality traits element influenced (perceived) investment performance. The purpose of this research was to test how the Big Five personality qualities affected (perceived) investment performance. The hypotheses were tested using PLS-SEM. Individual stock investors in Indonesia were studied, and the results revealed that openness and neuroticism personality had a negative impact on (perceived) investment performance. Consciousness, extraversion, and agreeableness, on the other hand, all had a positive effect on (perceived) investment performance. This research shows the importance of personality traits when allocating assets to meet investment objectives and improves behavioral finance theory.

6.
International Journal of Professional Business Review ; 8(4), 2023.
Article in English | Scopus | ID: covidwho-2315125

ABSTRACT

Purpose: The purpose of this research is to find out the MSME Sustainability Strategy after the Covid-19 pandemic by analyzing the role of crowdfunding and the digital market by improving MSME performance using the Canvas Model Business Strategy as an Intervening Variable. Theoretical framework: The latest literature has not explained the MSME Sustainability Strategy after the Covid-19 pandemic By Analyzing the Role of Crowdfunding and the Digital Market by Improving MSME Performance Using the Canvas Model Business Strategy as an Intervening Variable. Design/methodology/approach: This research uses a Mix Method research approach, which is a combination of quantitative and qualitative combinations. By using the combined method, it is expected to be able to complement each other from the existing hypotheses. Quantitative emphasizes the technical analysis of statistical tests so that the data is more accurate, and qualitative techniques emphasize the analysis of the process of inductive thinking processes related to the dynamics of the relationship between observed phenomena and always use scientific logic. Findings: there has been an increase in the performance of MSMEs, namely changes in (1) technological innovation using sales methods from direct sales to online sales, (2) Human Relations, namely synergizing with various Croudfunding and BUMN parties in overcoming capital problems, (3) Absorption of labor work, (4) Market Adaptation and (5) Managerial dynamism and financial ratios that change for the better. Research, Practical & Social implications: Researchers suggest MSMEs cooperate with Crowdfunding and Digital Markets for business sustainability. Originality/value: The results show that these 5 aspects have increased, namely 1) Aspects of sales increased by 23% 2) Aspects of operating profit increased by 25%. 3) Capital aspect increased by 30% 4) the Aspect of the number of employees 10% and 5) the Aspect of bank installment payment ability increased by 5%. © 2023 EDIZIONI MINERVA MEDICA.

7.
Med Sci Monit ; 29: e939797, 2023 May 12.
Article in English | MEDLINE | ID: covidwho-2318857

ABSTRACT

BACKGROUND The Indonesian Chronic Disease Management Program (PROLANIS) is a government program that aims to improve the health outcomes of patients with chronic diseases, including hypertension. This preliminary study aimed to evaluate the impacts of the coronavirus disease 2019 (COVID-19) pandemic on the health outcomes of hypertension patients in rural areas who were enrolled in PROLANIS. MATERIAL AND METHODS This study used data from 4 PROLANIS groups in East Java province. The data were collected from participants' 6-month evaluations at 3 time points: before the COVID-19 pandemic in December 2019 (T0), during the COVID-19 pandemic in June 2020 (T1), and in December 2020 (T2). Evaluated parameters were body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol (TC), low-density lipid (LDL), high-density lipid (HDL), triglyceride (TG), and estimated glomerular filtration rate (eGFR). RESULTS There were 91 patients included in the analyses. Compared to T0, BMI, blood pressure, eGFR, and TC had significantly deteriorated at T1, but LDL, HDL, and TG showed no marked changes. At T2, BMI, DBP, and TC were similar to T0. On the other hand, SBP and eGFR did not improve, while HDL significantly deteriorated. Stratified based on age, worsening of DBP, TC, and LDL at T1 and eGFR at T1 and T2 was only observed in those aged 60 years and older. CONCLUSIONS This preliminary study showed that the health outcomes of hypertension patients in rural areas who were enrolled in PROLANIS were negatively impacted during the COVID-19 pandemic, with the elderly being the most affected.


Subject(s)
COVID-19 , Hypertension , Aged , Humans , Middle Aged , Indonesia/epidemiology , Pandemics , Hypertension/epidemiology , Hypertension/therapy , Triglycerides , Blood Pressure/physiology , Disease Management , Cholesterol, HDL
8.
Psikhologicheskaya Nauka I Obrazovanie-Psychological Science and Education ; 28(1):122-131, 2023.
Article in English | Web of Science | ID: covidwho-2310171

ABSTRACT

The present study reported a life experience of a teacher family in Indonesia with a 4-year-old daughter. The observation occurred from March 2020 to July 2021 during the COVID-19 pandemic. This stay-at-home moment became an opportunity to create more parent-kid preschooler bonding and interaction that could impact the developing children language. Indonesian is our family native language (L1);therefore, the exposure started earlier for the kids. However, as parent-kid interaction was enhanced during the pandemic, we boosted our kid English (L2) with a variety of Edu-home activities such as reading aloud, storytelling, role-playing, and watching YouTube-kid. Her language production was documented, and the progress was analyzed. The aim was to generate a more profound understanding of our roles as parents in scaffolding the acceleration of preschoolers' English development, especially in creating meaningful activities. Going through an autoethnography, we reflect on our practice to know how the family members played the role of a language catalyst and which activities were taken more into account.

9.
Malaysian Journal of Medicine and Health Sciences ; 19:19-22, 2023.
Article in English | Scopus | ID: covidwho-2293849

ABSTRACT

Introduction: IL-12 and IL-10 are cytokines with different mechanisms in the pathogenesis of COVID-19. Differences in IL-12 and IL-10 levels in patients receiving convalescent plasma and non-convalescent plasma recipients need to be known because the total levels of IL-12 and IL-10 also determine the clinical condition of the patient. Materials and Methods: This study used 40 randomly selected blood serum samples with details of 20 samples of COVID-19 patients without convalescent plasma therapy and 20 samples of COVID-19 patients. The COVID-19 patients at the Haji General Hospital in Surabaya provided the patient serum that was utilized. Results: Based on the findings, there were differences in IL-10 levels between the control group and convalescent plasma therapy recipients (P<0.05). On IL-12 levels had no difference between the control and treatment groups (P>0.05). Conclusion: According to statistical estimates, convalescent plasma treatment made a difference to IL-10 but not IL-12 levels in COVID-19 patients. © 2023 UPM Press. All rights reserved.

10.
Malaysian Journal of Medicine and Health Sciences ; 19:54-56, 2023.
Article in English | Scopus | ID: covidwho-2292681

ABSTRACT

Introduction: The preferred treatment for COVID-19 cases is Convalescent Plasma. In COVID-19 patients, cytokine storms are caused by high levels of cytokines including: Inflammatory cytokines such as (IL-10, IL-12, IL-27, IL-21, TNF-α and IFN-γ, IL-2, and IL-6), are triggered by T cell responses. The goal of this research is to determine Does administration of convalescent plasma affect the TNF-α and IFN-γ cases of COVID-19 sufferers. Materials and methods: The experimental research method uses (a post-test only control group design). The study material in the form of serum from the blood of COVID-19 patients as many as 38 samples selected randomly with details of COVID-19 patients as many as 19 samples were not given convalescent plasma treatment and 19 samples of COVID-19 patients receiving convalescent plasma therapy. Results: This study showed that there was no effect on TNF-α levels before and after convalescent plasma administration (P> 0.05), while IFN-γ levels showed an effect between before and after convalescent plasma administration (P< 0.05). Conclusion: Although in this study there were differences in the results of statistical analysis of TNF-α and IFN-γ levels in convalescent plasma treatment of COVID-19 patients, this study proved to be able to improve the clinical condition of COVID-19 cases. © 2023 UPM Press. All rights reserved.

11.
6th International Conference on Information Technology and Digital Applications, ICITDA 2021 ; 2508, 2023.
Article in English | Scopus | ID: covidwho-2301039

ABSTRACT

SARS-Cov-2 spreads quickly and continues to do so to this day. One way to limit the spread is by limiting people's mobility through transportation. The Provincial Government of Jakarta has implemented the Large-Scale Social Restriction Transitional Phase-1 since June 5th, 2020, to limit people mobility and the odd-even policies August 3rd, 2020, to limit private vehicles. To assess the effectiveness of these policies against the positivity rate of COVID-19 cases in Jakarta, we used data exploration and significant tests (pre-and post-condition). The result shows that the odd-even policy significantly impacts private transportation mobility, mobility in public transportation, and the COVID-19 positivity rate in Jakarta. The relationship between those three parameters is linearly significant. The odd-even policy stimulates people to switch from private to public transportations and increases the positivity rate of COVID-19. The odd-even policy effectively reduces the mobility of private transportation but insignificantly reduces the positivity rate of COVID-19 in Jakarta. The results can be used as insights for policy decision-makers to manage the COVID-19 pandemic. © 2023 Author(s).

12.
Pharmacognosy Journal ; 15(1):171-174, 2023.
Article in English | EMBASE | ID: covidwho-2297381

ABSTRACT

Background: One of the efforts to control SARS-CoV-2 infection in health workers is vaccination. In this study, the levels of SARS-CoV-2 neutralizing antibody (nAb) in health workers were measured with Ichroma and iFlash. Method(s): This study applied an observational analytic design with a prospective cohort and was conducted at Dr. Soetomo Regional Public Hospital, Surabaya, from January to November 2021. The population of this study included a total of 75 health workers after taking the second dose of the SARS-CoV-2 (Sinovac) vaccine. The Covid-19 NAb levels of the population were tested with Ichroma and iFlash on day 0 before vaccination, as well as days 14 and 28, and months 3 and 6 after vaccination. Result(s): The Friedman test indicated a significant difference in NAb levels according to the iFlash test on day 14, day 28, month 3, and month 6 compared to those before vaccination (p < 0.05). The Wilcoxon test revealed a significant difference in NAb levels on day 14, day 28, month 3, and month 6. The results of the Cochran test showed a significant difference in the positivity of NAb according to the Ichroma test on day 14, day 28, month 3, and month 6 compared to those before vaccination (p < 0.05). McNemar's test demonstrated that the COI at month 3 was not significantly different from that before vaccination;The COI at month 6 was not significantly different from those at days 14 and 28. The results of the Pearson correlation test and Bland-Altman plot indicated a moderate correlation between Ichroma and iFlash (r = 0.592, p = 0.002). Conclusion(s): Neutralizing antibodies for Covid-19 were formed after day 14 and started to increase on day 28 and started to decrease in months 3 and 6. The levels of NAb for Covid-19 were measured with Ichroma and iFlash in roughly the same pattern and had a moderate positive correlation.Copyright © 2023 Phcogj.Com.

13.
Ann Med Surg (Lond) ; 85(4): 802-806, 2023 Apr.
Article in English | MEDLINE | ID: covidwho-2304533

ABSTRACT

Studies evaluating the levels of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) anti-spike protein receptor-binding domain (S-RBD) immunoglobulin G (IgG) antibodies in vaccinated healthcare workers in Indonesia are limited. Objectives: Evaluating time-dependent levels of anti-IgG S-RBD antibodies and monitoring the response of healthcare workers in a tertiary hospital in Indonesia after vaccination. Materials and methods: This prospective cohort observational study was conducted from January to December 2021. A total of 50 healthcare workers participated in the study. Blood samples were collected at five time points. Antibody levels were measured using a CL 1000i analyzer (Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, China). Antibody levels between groups were analyzed using the Wilcoxon signed-rank test with P less than 0.05. Results: The median levels of SARS-CoV-2 anti-S-RBD IgG antibody on days 14, 28, 90, and 180 were significantly higher than the levels on day 0 (P<0.001). After the second dose, peak levels were observed on day 14; the levels decreased gradually after day 28. Despite receiving two doses of the vaccine, 10 out of 50 participants (20%) were infected with COVID-19 (coronavirus disease 2019). However, symptoms were mild, and antibody levels were significantly higher than in noninfected participants (P<0.001). Conclusion: SARS-CoV-2 anti-S-RBD IgG antibody levels increased significantly until day 14 after the second dose; the levels decreased gradually after day 28. Ten participants (20%) were infected with SARS-CoV-2, with mild symptoms.

14.
Ann Med Surg (Lond) ; 85(4): 1276-1281, 2023 Apr.
Article in English | MEDLINE | ID: covidwho-2291111

ABSTRACT

The authors reported two patients with a history of asymptomatic mild mitral valve prolapse, a male in his late 40s (Case 1, vaccinated) and a female in her late 20s (Case 2, unvaccinated), who developed worsening (severe) mitral prolapse and New York Heart Association symptoms class III-IV after exposure to coronavirus disease 2019 with evidence of myocarditis on MRI. Both patients received similar 6-month of heart failure therapy; however, the outcomes did not affect the severity of their symptoms or mitral regurgitation. Subsequently, both patients underwent mitral valve surgery.

15.
Heliyon ; 9(4): e15122, 2023 Apr.
Article in English | MEDLINE | ID: covidwho-2294701

ABSTRACT

Background: COVID-19 cases surge, it has a crucial impact on healthcare systems, with rapidly increasing demand for healthcare resources in hospitals and intensive care units (ICUs) in Indonesia and worldwide. It is necessary to quantify the extent to which the effects of the COVID-19 pandemic on the hospital admissions, and clinical and financial outcomes of patients with non-COVID-19 respiratory symptoms. Objective: To determine whether the COVID-19 pandemic changed the hospitalisation of child and adult patients with non-COVID-19 respiratory conditions and whether these changes affected the patient's disease condition, clinical outcomes, and hospital finances. Methods: A retrospective cohort study was conducted from May 1, 2018 (before the COVID-19 pandemic) until December 31, 2021. Total sampling was done to compare hospital admission of patients with non-COVID-19 respiratory symptoms before versus during the COVID-19 pandemic. The results were analyzed using SPSS 26.0 and SmartPLS.v.3.2.9. Results: There was a reduction in hospitalisations for respiratory disorders unrelated to COVID-19 during the pandemic by 55.3% in children and 47.8% in adult patients. During the pandemic, the average hospital revenue per patient of child and adult patients increased significantly, but the profit per patient decreased. Pathway analysis showed that in children, the COVID-19 Pandemic changed disease severity and complexity (ß = 0.132, P < 0.001), as well as clinical outcomes (ß = 0.029, P < 0.05). In adults, the COVID-19 pandemic improves disease severity and complexity (ß = -0.020, P < 0.001), as well as clinical outcomes (ß = -0.013, P < 0.001). COVID-19 pandemic increases care charges (in children with ß = 0.135, P < 0.001; and in the adult patients with ß = 0.110, P < 0.001), worsens hospital financial outcomes relating to child (ß = -0.093, P < 0.001) and adult patient (ß = -0.073, P < 0.001). In adult patients, seasonal variations moderate the impact of the COVID-19 pandemic on improving disease conditions (ß = -0.032, P=<0.001). The child structural model effectively predicted clinical outcomes (Q2 = 0.215) and financial outcomes (Q2 = 0.462). The adult structural model effectively predicted clinical outcomes (Q2 = 0.06) and financial outcomes (Q2 = 0.472). Conclusion: The conclusions are that the number of non-COVID respiratory patients decreased during the COVID-19 pandemic (47.8% in adult patients, 55.3% in child patients). Disease severity and complexity increased in child patients but decreased in adult patient. Costs of care and insurance payments increased. Since the insurance payments did not increase as much as the cost of care, hospital profit decreased.

16.
Pharmacognosy Journal ; 14(6 Suppl):887-892, 2022.
Article in English | CAB Abstracts | ID: covidwho-2267641

ABSTRACT

Background: COVID-19 has spread rapidly around the world. It is necessary to study lung tissue of postmortem COVID19 patients to determine the molecular alteration particularly the role of IL-6 and IL-17 in causing fatality. Background: This study aims to determine the differences in the expressions of IL-6 and IL-17 in lung tissue of post-mortem COVID-19 patients compared to non-COVID-19 patients. This study also aimed to analyze the correlation between the expressions of IL-6 and IL-17 in lung tissue of post-mortem COVID-19 patients. Methods: This research is an observational analytic study with crosssectional approach. The samples were 15 paraffin blocks of post-mortem lung tissue biopsy of COVID-19 patients, and 15 paraffin blocks of inflammatory lung tissue biopsy or surgery of non-COVID-19 patients. IL-6 and IL-17 expressions were evaluated by immunohistochemical procedure. Result: There was a significant difference in the expression of IL-6 in the COVID-19 group and the non-COVID-19 group with a p-value = 0.001 (p < 0.05). There was a significant difference in the expression of IL-17 in the COVID-19 group and the non-COVID-19 group with p-value = 0.001 (p < 0.05). There was a significant correlation between the expressions of IL-6 and IL-17 in the COVID-19 group, with the Spearman coefficient value (rs) of 0.548 with p = 0.034 (p < 0.05). Conclusion: There are differences in the expression of IL-6 and IL-17 between COVID-19 and non-COVID-19 lung tissue. There is a significant correlation between the expressions of IL-6 and IL-17 in post-mortem lung tissue of COVID-19 patients.

17.
4th International Conference Advancement in Data Science, E-Learning and Information Systems, ICADEIS 2022 ; 2022.
Article in English | Scopus | ID: covidwho-2266549

ABSTRACT

The use of private vehicles during the Covid-19 pandemic has increased because private vehicles, especially cars, are considered as the safest mode of transportation to maintain distance and prevent transmission of the Covid-19 virus. Based on data from two different Indonesian secondary car market place, a comparison of a price sample of Car X in the city of Surabaya with the specifications for the 2015 to 2018 car years with car milage under 1000 kilometers, the used cars have a variety of prices hence a used car price prediction system is needed so that people can find out the average price of used cars sold in the market. In this study the author will use the Random Forest Regressor as a machine learning algorithm to predict the price of a used car with a dataset from the AtapData website. The reason for choosing the Random Forest Regressor is because the algorithm has the power to handle large amounts of data with high dimensions with categorical and numerical data types. The evaluation method used in this study is the Root Mean Absolute Error which produces a value of 0.55612 for validation data and 0.56638 for testing data, while the evaluation proceed with Mean Absolute Error produces a value of 0.45208 for validation data and 0.47576 for testing data. © 2022 IEEE.

18.
4th International Conference on Vocational Education of Mechanical and Automotive Technology, ICoVEMAT 2021 ; 2671, 2023.
Article in English | Scopus | ID: covidwho-2262249

ABSTRACT

Problem-solving skills are part of Critical Thinking which focuses on the student's abilities to face the 21st century. Recently, one technique to foster and improve problem-solving skills is by learning through Computational Thinking. Many previous studies have described that Computational Thinking is a problem-solving technique adopted from Computer Sciences. However, Computational Thinking learning had been carried out in class or asynchronous. The COVID-19 situation raises the challenges of how Computational Thinking can be taught online. Therefore, this study aims to develop an instructional design in online-based computational thinking learning. The development of this study employs the ADDIE method. The final step of the development stage was carried out through a small-scale online class experiment. The development result obtained by Scratch, which is an online programming platform that is suitable for 1) learning Computational Thinking, 2) instructional design that refers to problem-based learning, and 3) instructional strategies that refer to Bloom's taxonomy. The results of the small-scale instructional design experiment showed that there was a significant improvement in the students' ability in problem-solving and computational thinking. © 2023 Author(s).

19.
4th International Conference Advancement in Data Science, E-Learning and Information Systems, ICADEIS 2022 ; 2022.
Article in English | Scopus | ID: covidwho-2262156

ABSTRACT

Due to the Covid-19 plague, children with hearing misfortune have experienced challenges in learning and practicing sign language due to need of educational services and learning assets. The next considerations for creating an educational mobile learning application to help deaf kids learn Malaysian Sign Language (MSL). The investigation was conducted through gatherings based on inquire about and interviews with subject matter experts. Instructors recommend that within the current circumstance, versatile learning application are the foremost reasonable stage for understudies to memorize or as an extra learning strategy in arrange to educate them well. This research was conducted through research-based and interview sessions with subject matter experts and followed the Multimedia Mobile Content Development (MMCD) methodology as it was shown to help accelerate development activities and ensure that the application would work and execute as planned. Once the application is developed, students from Sekolah Kebangsaan Silabukan in Lahad Datu, Sabah, will participate in beta testing. Based on the results of user acceptance tests, the application has received positive reviews from its target users. As such, the project's goals are said to have been achieved. At the conclusion of the study, the advantages, limitations and future work of Pocket Sign Language were also identified. © 2022 IEEE.

20.
Heliyon ; 2023.
Article in English | EuropePMC | ID: covidwho-2258242

ABSTRACT

Background COVID-19 cases surge, it has a crucial impact on healthcare systems, with rapidly increasing demand for healthcare resources in hospitals and intensive care units (ICUs) in Indonesia and worldwide. It is necessary to quantify the extent to which the effects of the COVID-19 pandemic on the hospital admissions, and clinical and financial outcomes of patients with non-COVID-19 respiratory symptoms. Objective To determine whether the COVID-19 pandemic changed the hospitalisation of child and adult patients with non-COVID-19 respiratory conditions and whether these changes affected the patient's disease condition, clinical outcomes, and hospital finances. Methods A retrospective cohort study was conducted from May 1, 2018 (before the COVID-19 pandemic) until December 31, 2021. Total sampling was done to compare hospital admission of patients with non-COVID-19 respiratory symptoms before versus during the COVID-19 pandemic. The results were analyzed using SPSS 26.0 and SmartPLS.v.3.2.9. Results There was a reduction in hospitalisations for respiratory disorders unrelated to COVID-19 during the pandemic by 55.3% in children and 47.8% in adult patients. During the pandemic, the average hospital revenue per patient of child and adult patients increased significantly, but the profit per patient decreased. Pathway analysis showed that in children, the COVID-19 Pandemic changed disease severity and complexity (β = 0.132, P < 0.001), as well as clinical outcomes (β = 0.029, P < 0.05). In adults, the COVID-19 pandemic improves disease severity and complexity (β = -0.020, P < 0.001), as well as clinical outcomes (β = −0.013, P < 0.001). COVID-19 pandemic increases care charges (in children with β = 0.135, P < 0.001;and in the adult patients with β = 0.110, P < 0.001), worsens hospital financial outcomes relating to child (β = −0.093, P < 0.001) and adult patient (β = −0.073, P < 0.001). In adult patients, seasonal variations moderate the impact of the COVID-19 pandemic on improving disease conditions (β = −0.032, P=<0.001). The child structural model effectively predicted clinical outcomes (Q2 = 0.215) and financial outcomes (Q2 = 0.462). The adult structural model effectively predicted clinical outcomes (Q2 = 0.06) and financial outcomes (Q2 = 0.472). Conclusion The conclusions are that the number of non-COVID respiratory patients decreased during the COVID-19 pandemic (47.8% in adult patients, 55.3% in child patients). Disease severity and complexity increased in child patients but decreased in adult patient. Costs of care and insurance payments increased. Since the insurance payments did not increase as much as the cost of care, hospital profit decreased.

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